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Syphilis During Pregnancy: Symptoms, Risks and Prevention

SYPHILIS (SIFILIS) • HEALTH GUIDE

Syphilis During Pregnancy: Symptoms, Risks and Prevention

Nexus Laboratories health information team • Updated 8 October 2026

Syphilis during pregnancy needs prompt medical care even if there are no symptoms. Screening and timely treatment help protect both the pregnant person and the baby.

A pregnant adult speaking with an antenatal clinician
Illustrative photo for Syphilis During Pregnancy: Symptoms, Risks and Prevention. People pictured do not represent anyone’s STI status.

Why antenatal screening matters

Syphilis can pass to a baby during pregnancy and cause serious complications, including pregnancy loss and congenital infection. Tell your antenatal team about previous syphilis treatment, possible exposure or a partner's diagnosis.

Treatment should not be delayed

Penicillin is the treatment with documented effectiveness for preventing congenital syphilis. A reported allergy requires specialist assessment rather than substituting a home remedy. The clinician chooses the regimen and checks whether the baby needs assessment.

A practical prevention plan

Attend antenatal appointments, ask about your screening results and discuss any new exposure. Repeat testing may be appropriate according to risk and local guidance. Partner care is essential to reduce the chance of reinfection during pregnancy.

Frequently asked question

Is a negative early pregnancy test enough after a new exposure?

Not necessarily. Tell your antenatal team about a later exposure so they can advise repeat testing and care.

Useful next steps for readers in Malaysia

Use this guide to prepare questions for a healthcare professional. Bring your exposure dates, symptoms, test results and any treatment records. Ask what the result means, whether you need another test and how follow-up will be arranged.

This is general health information, not an individual diagnosis. Seek urgent care for new vision, hearing or neurological problems; contact your antenatal team promptly about a possible exposure during pregnancy.

Related guides

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